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Binay Krishna Ghorai

About


I have received B.Sc. (Hons) in Chemistry (1986) from the University of Calcutta, M.Sc. in Chemistry (1989) from the Indian Institute of Technology, Kharagpur. Then I have joined in the doctoral programme in the same Institute under the guidance of Prof. Tarun Kumar Sarkar and worked in the area of Synthetic Organic and Organometallic Chemistry. After receiving the Ph.D. degree (1995), I moved to this Institute (the then Bengal Engineering College, A Deemed University) as a Lecturer and continuing as a faculty of this Institute. I did postdoctoral research work at the Department of Chemistry and Biochemistry, New Mexico State University, New Mexico, USA with Professor J. W. Herndon during the period 2000–2002 (two-years) and worked using Fischer carbene chemistry.

My research interests mainly focus on the synthesis of nitrogen heterocycles of biological importance, and molecular design and synthesis of organic π-conjugated materials for optoelectronic & bio-sensing applications.

Academic Qualifications


  • Ph.D. (01/1995), Indian Institute of Technology, Kharagpur
    Thesis: Studies on Alder-Ene Reactions and σ-Allylmetallics of Silicon: Total Synthesis of Cyclopentanoid Natural Products.
    Advisor: Professor T. K. Sarkar
  • M.Sc. Chemistry, 1989, Indian Institute of Technology, Kharagpur
  • B.Sc. (Hons) Chemistry, 1986 (result published in 1987), Calcutta University

Research Statement


  • Synthetic Organic and Organometallic Chemistry; Heterocyclic Chemistry: Reactions involving Fischer carbene-chromium complexes and alkynes have emerged as a powerful tool for synthetic organic chemists, allowing for the direct synthesis of a variety of natural molecules. Our Group worked on this chemistry and has developed a novel and interesting method for the generation of heteroaromatic isobenzofurans in situ, which were trapped with suitable dienophiles leading to the synthesis of series of complex azaheterocycles, namely, heterolignanes, phenazines, quinoxaline derivatives,  quinazolines, furo[2,3-h]quinolines, furo[2,3-h]isoquinoline derivatives, azafuranophane derivatives, azahomosteroids etc.
  • Molecular Design and Synthesis of Organic π-Conjugated Materials for Optoelectronic & Bio-sensing Applications: Presently our Group focussed on the design, synthesis, characterization and studies on the optoelectronic properties of highly branched molecular architectures, now commonly known as p-conjugate oligomers, which have emerged to become a key element in the research efforts of scientist worldwide. Many applications have been claimed for this new type of compounds, namely, bio-sensing materials i.e. potential vehicles for delivery of druges and immunogens and optoelectrical properties. 

Latest Publications


  • 1 R. Majumder, D. Jana, B. K. Ghorai, Synthesis of V-shaped Thiophene Based Rotor-Stilbene: Substituent Dependent Aggregation and Photophysical Properties, Journal of Fluorescence, 2024
  • 2 R. Majumder, D. Jana, B. K. Ghorai, Fluorene-based conjugates with geminal donor-acceptor: synthesis, photophysical properties and theoretical studies, Journal of Chemical Sciences, 2024
  • 3 S Mandal, D Jana, J Dolai, AK Sarkar, BK Ghorai, NR Jana, Biodegradable Poly (trehalose) Nanoparticle for Preventing Amyloid Beta Aggregation and Related Neurotoxicity, ACS Applied Bio Materials, 2023
  • 4 R Majumder, S Dey, D Jana, BK Ghorai, Donor-acceptor cyanostilbene based nano-AIEgens: Synthesis and properties, 5, 100856, Results in Chemistry, 2023
  • 5 P. Mondal, S. Biswas, D. Jana, B. Das, U. K. Ghorai, B. K. Ghorai, S. Acharya, Aggregation induction of tetraphenylethylene AIEgen and its supramolecular aggregates toward light-emitting diodes, 282, 121122, Journal of Solid State Chemistry, 2020
  • 6 K. Mandal, D. Jana, B. K. Ghorai, N. Jana, AIEgen-Conjugated Magnetic Nanoparticles as Magnetic-Fluorescent Bioimaging Probes, 2, 3292-3299, ACS Appl. Nano Mater., 2019
  • 7 S. Boxi, D. Jana, B. K. Ghorai, Synthesis and Optical Properties of Bipolar Quinoxaline-Triphenylamine Based Stilbene, Optical Materials, 2019
  • 8 S. Boxi, D. Jana, P. P. Parui, B. K. Ghorai, Dibenzo[a,c]phenazine based donor-acceptor (D-A) tetra branched molecules: Fine tuning of optical properties, 3, 6953-6959, Chemistry Select., 2018
  • 9 S. Biswas, D. Jana, G. Kumar, S. Maji, P. Kundu, U. Ghorai, R. Giri, B. Das, N. Chattopadhyay, B. K; Ghorai, S. Acharya, Supramolecular Aggregates of Tetraphenylethene Cored AIEgen towards Mechanoluminescent and Electroluminescent Devices, 10(3), 14966–14977, ACS Appl. Mater. Interfaces, 2018
  • 10 K. Mandal, D. Jana, B. K. Ghorai, N. R. Jana, Functionalized chitosan with self-assembly induced and subcellular localization-dependent fluorescence ‘switch on’ property, 42(1), 5774-5784, New J. Chem., 2018
  • View More

    Publications


  • 1 R. Majumder, D. Jana, B. K. Ghorai, Synthesis of V-shaped Thiophene Based Rotor-Stilbene: Substituent Dependent Aggregation and Photophysical Properties, Journal of Fluorescence, 2024
  • 2 R. Majumder, D. Jana, B. K. Ghorai, Fluorene-based conjugates with geminal donor-acceptor: synthesis, photophysical properties and theoretical studies, Journal of Chemical Sciences, 2024
  • 3 S Mandal, D Jana, J Dolai, AK Sarkar, BK Ghorai, NR Jana, Biodegradable Poly (trehalose) Nanoparticle for Preventing Amyloid Beta Aggregation and Related Neurotoxicity, ACS Applied Bio Materials, 2023
  • 4 R Majumder, S Dey, D Jana, BK Ghorai, Donor-acceptor cyanostilbene based nano-AIEgens: Synthesis and properties, 5, 100856, Results in Chemistry, 2023
  • 5 P. Mondal, S. Biswas, D. Jana, B. Das, U. K. Ghorai, B. K. Ghorai, S. Acharya, Aggregation induction of tetraphenylethylene AIEgen and its supramolecular aggregates toward light-emitting diodes, 282, 121122, Journal of Solid State Chemistry, 2020
  • 6 K. Mandal, D. Jana, B. K. Ghorai, N. Jana, AIEgen-Conjugated Magnetic Nanoparticles as Magnetic-Fluorescent Bioimaging Probes, 2, 3292-3299, ACS Appl. Nano Mater., 2019
  • 7 S. Boxi, D. Jana, B. K. Ghorai, Synthesis and Optical Properties of Bipolar Quinoxaline-Triphenylamine Based Stilbene, Optical Materials, 2019
  • 8 S. Boxi, D. Jana, P. P. Parui, B. K. Ghorai, Dibenzo[a,c]phenazine based donor-acceptor (D-A) tetra branched molecules: Fine tuning of optical properties, 3, 6953-6959, Chemistry Select., 2018
  • 9 S. Biswas, D. Jana, G. Kumar, S. Maji, P. Kundu, U. Ghorai, R. Giri, B. Das, N. Chattopadhyay, B. K; Ghorai, S. Acharya, Supramolecular Aggregates of Tetraphenylethene Cored AIEgen towards Mechanoluminescent and Electroluminescent Devices, 10(3), 14966–14977, ACS Appl. Mater. Interfaces, 2018
  • 10 K. Mandal, D. Jana, B. K. Ghorai, N. R. Jana, Functionalized chitosan with self-assembly induced and subcellular localization-dependent fluorescence ‘switch on’ property, 42(1), 5774-5784, New J. Chem., 2018
  • 11 K. Mandal, D. Jana, B. K. Ghorai, N. R. Jana, Fluorescent Imaging Probe from Nanoparticle Made of AIE Molecule, 120(19), 5196?5206, J. Phys. Chem. C, 2016
  • 12 N. Pradhan, D. Jana, B. K. Ghorai, N. Jana, Detection and Monitoring of Amyloid Fibrillation Using Fluorescence ‘Switch-On’ Probe, 7(19), 25813?25820, ACS Appl. Mater. Interfaces, 2015
  • 13 D. Jana, S. Boxi, P. P. Parui, B. K. Ghorai, Planar-Rotor architecture based pyrene-vinyl-tetraphenylethylene conjugated systems: photophysical properties and aggregation behavior, 13, 10663–10674, Org. Biomol. Chem., 2015
  • 14 D. Jana, B. K. Ghorai, Side substituent dependence of photophysical properties of 9-arylanthracene based ?-conjugates, 88, 89–96, Bull. Chem. Soc. Jpn., 2015
  • 15 D. Jana, B. K. Ghorai, Hexaphenylbenzene end-capped tri(p-phenylenevinylene): Synthesis and properties, 55(3), 5203–5206, Tetrahedron Lett., 2014
  • 16 D. Jana, S. Boxi, B. K. Ghorai, Synthesis of gem-tetraphenylethylene oligomers utilizing Suzuki reaction and their aggregation properties, 99(10), 740–747, Dyes and Pigments, 2013
  • 17 P. Roy, P. Mitra, B. K. Ghorai, Synthesis of azahomosteroid ring system through intramolecular [4+2] cycloaddition of in situ generated azaisobenzofuran intermediates, 54(7), 1440–1443, Tetrahedron Lett., 2013
  • 18 D. Jana, B. K. Ghorai, Synthesis and aggregation-induced emission properties of tetraphenylethylene–based oligomers containing triphenylethylene moiety, 53(29), 6838–6842, Tetrahedron Lett., 2012
  • 19 D. Jana, B. K. Ghorai, Pyridine–cored V–shaped ?–conjugated oligomers: synthesis and optical properties, 68(15), 7309–7316, Tetrahedron, 2012
  • 20 D. Jana, B. K. Ghorai, Triphenylpyridine-based star-shaped ?-conjugated oligomers with triphenylamine core: Synthesis and photophysical properties, 53(9), 1798–1801, Tetrahedron Lett., 2012
  • 21 D. Jana, B. K. Ghorai, Synthesis and fluorescence behaviour of star-shaped pyridine and benzene cored stilbenoid compounds, 405–410, 405–410, J. Indian Chem. Soc., 2012
  • 22 P. Roy, B. K. Ghorai, One-pot synthesis of pyrano[4,3-b]quinolinones from 2-alkynyl-3-formylquinolines via oxidative 6-endo-dig ring closure, 53(7), 235–238, Tetrahedron Lett., 2012
  • 23 D. Jana, B. K. Ghorai, Synthesis and photophysical properties of tetraphenylethylene-based conjugated dendrimers with triphenylamine core, 53(15), 196–199, Tetrahedron Lett., 2012
  • 24 P. Roy, B. K. Ghorai, Annulation of furan-bridged 10-membered rings on N-heterocycles through [8+2] cycloaddition of dienylazaisobenzofurans and dimethyl acetylenedicarboxylate, 52(9), 5668–5671, Tetrahedron Lett., 2011
  • 25 P. J. P. Yadav, B. Maiti, B. K. Ghorai, P. U. Sastry, A. K. Patra, V. K. Aswal and P. Maiti, Thermoreversible Gelation of Poly(vinylidene fluoride-co-chlorotrifluoroethylene): Structure, Morphology, Thermodynamics, and Theoretical Prediction, 44(6), 3029–3038, Macromolecules, 2011
  • 26 S. Mukherjee, P. Roy, B. K. Ghorai, One-pot three-component synthesis of quinoxaline, quinazoline and phenazine ring systems using Fischer carbene complexes, 11, 1419–1426, Synthesis, 2011
  • 27 P. Roy, B. K. Ghorai, One-pot synthesis of furo[2,3-h]quinoline and furo[2,3-h]isoquinoline derivatives using Fischer carbene complex, 52(10), 251–253, Tetrahedron Lett., 2011
  • 28 P. J. P. Yadav, A. K. Patra, P. U. Sastry, B. K. Ghorai and P. Maiti, Solvent Retention, Thermodynamics, Rheology and Small Angle X-ray Scattering Studies on Thermoreversible Poly(vinylidene fluoride) Gels, 114(6), 11420–11429, J. Phys. Chem. B, 2010
  • 29 P. Roy, D. Jana, B. K. Ghorai, Synthesis and Photophysical Properties of Stilbenoid Dendrimers via Heck Reaction on a Tetraphenylethylene Core, 83(4), 1269–1271, Bull. Chem. Soc. Jpn., 2010
  • 30 G. P. Jana, S. Mukherjee, B. K. Ghorai, Multicomponent approach for the synthesis of phenanthridine and acridine ring systems via the coupling of Fischer carbene complexes with heteroaromatic o-alkynyl Carbonyl derivatives, 14, 3179–3189, Synthesis, 2010
  • 31 P. Roy, B. K. Ghorai, One-pot three-component synthesis of quinoxaline and phenazine ring systems using Fischer carbene complexes, 6(52), Beilstein J. Org. Chem., 2010
  • 32 S. Mukherjee, B. K. Ghorai, Metalation of 2,4-dialkoxy-5-bromopyrimidine and formylation with dimethylformamide: Isolation of unexpectedly formed 2,6-dialkoxy-5-dimethylaminopyrimidine-4-carboxaldehyde, 40, 1939–1943, Synth. Commun., 2010
  • 33 D. Jana, B. K. Ghorai, Design, Synthesis and Optical Response of Pyridine-Cored V-Shaped Stilbenoid Dendrimers, 7(2), 203–207, Lett. Org. Chem., 2010
  • 34 S. Mukherjee, G. P. Jana, B. K. Ghorai, Synthesis of isoquinolines through the coupling of Fischer carbene complexes with o-alkynylpyridine carbonyl derivatives, 694(11), 4100–4106, J. Organomet. Chem., 2009
  • 35 G. P. Jana, B. K. Ghorai, Tandem Generation and Trapping of Furo[3,4-c]isoquinoline Intermediates Leading to the Synthesis of Phenanthridine Ring Systems, 6(7), 372–376, Lett. Org. Chem., 2009
  • 36 G. P. Jana, B. K. Ghorai, Tandem furo[3,4-b]pyridine formation-Diels Alder reaction: an approach to the synthesis of nitrogen containing heterocyclic analogues of 1-arylnaphthalene lignans, 63(17), 12015–12025, Tetrahedron, 2007
  • 37 B. K. Ghorai, S. Duan, D. Jiang, J. W. Herndon, Coupling of ?-Cyanocarbene-Chromium Complexes with 2-Alkynylbenzoyl Derivatives: A [5+5]-Cycloaddition Approach to Phenanthridines, 21, 3661–3669, Synthesis, 2006
  • 38 B. K. Ghorai, D. Jiang, J. W. Herndon, Novel Synthesis of Isoquinolines Using Isobenzofuran- Nitriles Diels Alder Reactions, 5(33), 4261–4263, Organic Lett., 2003
  • 39 B. K. Ghorai, J. W. Herndon, Coupling of Fischer Carbene Complexes with o-Alkynylbenzamides, 22(21), 3951–3957, Organometallics, 2003
  • 40 B. K. Ghorai, S. Menon, D. L. Johnson, J. W. Herndon, Inversion of the Direction of Stereoinduction in the Coupling of Chiral g, d-Unsaturated Fischer Carbene Complexes with o-Ethynylbenzaldehyde, 4(22), 2121–2124, Organic Lett., 2002
  • 41 B. K. Ghorai, J. W. Herndon, Y.–F. Lam, One-Step Convergent Synthesis of the Steroid Ring System via the Coupling of ?, d-Unsaturated Fischer Carbene Complexes with o-Ethynylbenzaldehyde, 3(36), 3535–3538, Organic Lett, 2001
  • 42 T. K. Sarkar, B. K. Ghorai, Methyl Epijasmonate: Historical Perspective and Total Synthesis, 76(6), 693–706, J. Indian Chem. Soc., 1999
  • 43 T. K. Sarkar, P. Gangopadhyay, B. K. Ghorai, S. K. Nandy, J-M. Fang, Cyclopentanoid Allylsilane in Synthesis: A Facile Construction of the 5-8 Carbon Frame work of Asteriscanolide, 39(16), 8365–8366, Tetrahedron Lett, 1998
  • 44 T. K. Sarkar, B. K. Ghorai, S. K. Nandy, B. Mukherjee, A. Banerji, Stereochemical Control over three Contiguous Stereogenic Center in the Intramolecular Ene Reaction of activated 1,6-Dienes. Application to the Synthesis of (±)- Methyl Cucubate and (±)-Methyl Epijasmonate, 62(15), 6006–6011, J. Org. Chem, 1997
  • 45 T. K. Sarkar, B. K. Ghorai, S. K. Das, P. Gangopadhyay, P. S. V. Subba Rao, Siliocon as Controlling Element for Regioselective Ene Reaction of DEAD with (Homo)Allylic Silanes. Application to the Synthesis of Cyclic 1,2-Dinitrogen Compounds, 37, 6607–6610, Tetrahedron Lett, 1996
  • 46 T. K. Sarkar, S. K. Nandy, B. K. Ghorai, B. Mukherjee, Lithium Perchlorate Dispersed on Silica Gel, a Mild and Efficient Catalyst for Intramolecular Ene Reactions of Activated 1,6- and 1,7- Dienes, 10, 97–99, Synlett, 1996
  • 47 T. K. Sarkar, B. K. Ghorai, A. Banerji, Intramolecular Alder Ene Approach to Stereochemical Control over three Contiguous Stereogenic Centers: Synthesis of (±)- Methyl Cucubate and (±)-Methyl Epijasmonate, 35, 6907–6908, Tetrahedron Lett, 1994
  • 48 T. K. Sarkar, B. K. Ghorai, S. K. Nandy, B. Mukherjee, Intramolecular Alder Ene Reactions of activated 1,6-Dienes: Stereochemical Control over three Contiguous Stereogenic Centers, 35, 6903–6906, Tetrahedron Lett, 1994
  • 49 T. K. Sarkar, S. K. Ghosh, P. S. V. Subba Rao, B. K. Ghorai, An ‘Anomalous’ Ozonolysis of an Olefin: Isolation and Crystal Structure of Methyl (4aRS, 8RS, 8aRS)-Decahydro-2, 5-dioxo-quinoline-8-carboxylate, 3001–3014, J. Chem. Research(s), 1992 394–395 and J. Chem. Research(M), 1992
  • 50 T. K. Sarkar, B. K. Ghorai, Silicon-directed Bamford Stevens Reactions of ?- Trimethylsilyl N-Aziridinylimines, 20, 1184–1185, J. Chem. Soc., Chem. Commun., 1992
  • Patents


    # Patents Year

    Member


    Life Member (LM 9800825), FOSET, West Bengal
    Life Member (LM 3894), Indian Association for the Cultivation of Sciences (IACS)
    Life Member [F/6918 (LM)], Indian Chemical Society, Kolkata
    Life Member (LM 0582), Chemical Research Society of India (CRSI)

    Responsibilities


    Dean, Faculty Welfare
    05.04.2022 to Present
    Head, School of Management Sciences
    01.02.2021 -31.07.2021
    Professor In-Charge, Admission
    15.09.2020 - present
    Head of the Department, School of Community Science and Technology
    10.07. 2020 - 10.01.2021
    Member, Senate Under Graduate Committee (SUGC)
    2019-
    Chairman, Special Reservation Cell and Liasion Officer for SCs, STs and PwDs
    July 2018 to 06.02.2023
    Head of the Department, Centre of Excellence for Green Energy and Sensor Systems
    27.08.2019 to 12.03.2020
    Ph.D. Admission-in-Charge for AY 2020-21 (July cycle) and 2019-20 (July cycle and December cycle)
    01.02.2019 to 31.10.2020
    PI In-Charge CCMT and CCMN (2023, 2022,2021), Coordinator: M.Sc. Admission CCMN-2020 and CCMN-2019
    2023-24, 2022-23, 2021-22, 2020-21 and 2019-20 ac
    Head of the Department, Department of Chemistry
    16.12.2015 to 17.12.2017
    Member, Senate Committee for preparation of Ordinances for the Postgraduate Program (Vide office order No. RDO/25/18 dated 15.06.2018)

    Co-ordinator, DST-FIST project of the Department of Chemistry
    16.12.2015 to 17.12.2017

    Projects


    • Synthesis of ?-conjugated oligomers utilizing multi-fold Pd-catalyzed coupling reactions: Application to the organic electronic devices, Sponsored
      Completed
    • Design, Synthesis and Studies of Optoelectronic Properties of Stilbenoid Dendritic Compounds with Heteroaromatic Core, Sponsored
      Completed
    • Tandem azaisobenzofurans formation – Diels-Alder reactions: Applications to the synthesis of biologically active aromatic heterocycles, Sponsored
      Completed
    • Synthesis of aromatic nitrogen heterocycles by the coupling of the Fischer carbene complexes with heteroatom containing o- alkynyl benzoyl derivatives, Sponsored
      Completed
    • Fischer’s Carbene Complex: Applications to the synthesis of Heterolignanes and Conformationally Restricted Analogues of Biologically Important Nicotine and Anabasine, Sponsored
      Completed

    Awards


    • Certificate of Merit from CSIR, Year: 1989

    Research Groups


    Dr. Gouranga Prasad Jana
    Ph. D.
    gourangaprasadj@gmail.com

    Dr. Soumita Mukherjee
    Ph. D.
    besu.soumita@gmail.com

    Dr. P. Jaya Prakash Yadav
    Ph. D.
    jpyadav.palamari@gmail.com

    Dr. Priyabrata Roy
    Ph. D.
    priyo_chem@yahoo.co.in

    Dr. Debabrata Jana
    Ph. D.
    djana.besu@yahoo.com

    Dr. Samadrita Sengupta
    Ph. D.
    samadrita@yahoo.com

    Dr. Shatabdi Boxi
    Ph. D.
    sboxi.kolkata@gmail.com

    Riya Majumder
    Ph. D.
    majumderriya693@gmail.com

    Citations


    Google Scholar
    CITATION H-INDEX I-10 INDEX
    719 16 30
    Scopus
    DOCUMENTS CITATION H-INDEX
    48 699 17

    Created: 23 November 2019