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    Laksmikanta Adak

    Academic Qualifications


    • Assistant Professor - Indian Institute of Engineering Science and Technology, Shibpur, Howrah, India (March 2019 - Present)
    • Assistant Professor - Sovarani Memorial College, Affiliated to University of Calcutta, Howrah, India (June 2017 - March 2019)
    • Program-Specific Assistant Professor – Kyoto University, Japan (April 2016 - April 2017)
    • Post-Doctoral Research Fellow - Kyoto University, Japan (September 2014 - March 2016)
    • JSPS (Japan Society for the Promotion of Science) Postdoctoral Research Fellow - Kyoto University, Japan (September 2012 - August 2014)
    • Post-Doctoral Research Fellow - Nanyang Technological University, Singapore (January 2010 - May 2012)
    • Ph.D. in Science - Indian Association for the Cultivation of Science (degree obtained from Jadavpur University), Kolkata, India, 2010
    • M.Sc. (Organic Chemistry Special) - Vidyasagar University, India, 2005 [qualified GATE, NET-CSIR and placed among top 20%]
    • B.Sc. (Chemistry Honours) – from Midnapore College, affiliated to Vidyasagar University, India, 2003 (Gold Medalist)

    Latest Publications


  • 1 Sahoo, S.; Mandal, A.; Patra, A.; Adak, L., Palladium-Catalyzed Decarboxylative Cross-Coupling of 2,4-Dienoic Acids and Aryl Halides: Access to Fluorescence Active (E,E)?1,4- Diarylbutadienes, https://doi.org/10.1021/acs.joc.5c00782, J. Org. Chem., 2025
  • 2 Mondal, S.; Roy, K.; Pramanik, P.; Sahoo, S.; Kundu, P.; Saha, A.; Mondal, R.; Adak, L., Sustainable Mn-Assisted Cu-Catalyzed Cross-Coupling of Primary Amides and Sulfonamides with (Hetero)Aryl and Styryl Halides: Investigating a Novel Catalytically Active Species, doi.org/10.1002/asia.202500764, Chem Asian J., 2025
  • 3 Roy, K., Saha, A., Saha, B., Banerjee, S., Mukhopadhyay, C. D., Sahu, S. K., Adak, L., Reusable Iron?Copper Catalyzed Cross?Coupling of Primary Amides with Aryl and Alkyl Halides: Access to N?Arylamides as Potential Antibacterial and Anticancer Agents, 31, e202403649, Chem. Eur. J., 2025
  • 4 Saha, A., Roy, K., Mondal, S., Saha, B., Sumar, J., Sahu, S. K., Adak, L., Reusable cobalt–copper-catalyzed cross-coupling of (hetero) aryl halides with primary amides under air: investigating a new Co0/CoII-based catalytic cycle, 23, 5343-5351, Org. Biomol. Chem., 2025
  • 5 Panja, S.; Paul, B.; Saha, A.; Roy, K.; Nandi, C.; Majhi, B.; Adak, L.; Ranu, B. C., Ruthenium-Catalyzed Site-Selective Annulation of Benzoxazinones: An Easy Access to Dihydroisoquinoline Benzamide Derivatives, 31, e202500512, Chem. Eur. J., 2025
  • 6 Kundu, P.; Roy, K.; Saha, A.; Mondal, S.; Adak, L., Reusable, Efficient Manganese–Copper-Catalyzed Cross-Coupling of Aryl Halides with Aromatic Alcohols under Solvent-Minimized Conditions, 10, e01770, ChemistrySelect, 2025
  • 7 Saha, A.; Roy, K.; Banerjee, S.; Panja, S.; Khatua, M.; Mukhopadhyay; C. M., Samanta, S.; Adak, L., Room temperature palladium-catalyzed synthesis of novel unsymmetrical diamide scaffolds containing moieties of ?-ketoester as potential antibacterial, antifungal and anticancer Agents, 1322, 140177, Journal of Molecular Structure, 2025
  • 8 Roy, K.; Saha, A.; Sahoo, S.; Banerjee, Chitrangada Das Mukhopadhyay, Banerjee, S.; Adak, L., Reaction under Ball-Milling: Solvent-and Metal-Free One-Pot Diastereoselective Synthesis of Tetrahydroquinoline Derivatives as Potential Antibacterial and Anticancer Agents, 35, 2487-2495, Synlett, 2024
  • 9 Patel,A. R.; Maity, G.; Pati, T. K.; Adak, L.; Cioffi, C. L.; Banerjee, S., Hybrid Pd0.1Cu0.9Co2O4 nano-flakes: a novel, efficient and reusable catalyst for the one-pot heck and Suzuki couplings with simultaneous transesterification reactions under microwave irradiation, 12, 1496234, Frontiers in Chemistry, 2024
  • 10 Ranu, B. C.; Adak, L.; Mukherjee, N.; Ghosh, T., Benign-Metal-Catalyzed Carbon–Carbon and Carbon–Heteroatom Bond Formation, 34, 601-621, Synlett, 2023
    • View More

    Research Areas


    • Synthetic Organic Chemistry
    • Naturally abundant first-row transition metal catalysis (e.g., Mn, Fe, Co, Ni and Cu) and mechanistic investigation
    • Development of new reagents and methods for novel organic transformations
    • C–H bond activation/functionalization reactions, Asymmetric catalysis/synthesis
    • Green synthesis, heterogeneous catalysis

    Publications


  • 1 Sahoo, S.; Mandal, A.; Patra, A.; Adak, L., Palladium-Catalyzed Decarboxylative Cross-Coupling of 2,4-Dienoic Acids and Aryl Halides: Access to Fluorescence Active (E,E)?1,4- Diarylbutadienes, https://doi.org/10.1021/acs.joc.5c00782, J. Org. Chem., 2025
  • 2 Mondal, S.; Roy, K.; Pramanik, P.; Sahoo, S.; Kundu, P.; Saha, A.; Mondal, R.; Adak, L., Sustainable Mn-Assisted Cu-Catalyzed Cross-Coupling of Primary Amides and Sulfonamides with (Hetero)Aryl and Styryl Halides: Investigating a Novel Catalytically Active Species, doi.org/10.1002/asia.202500764, Chem Asian J., 2025
  • 3 Roy, K., Saha, A., Saha, B., Banerjee, S., Mukhopadhyay, C. D., Sahu, S. K., Adak, L., Reusable Iron?Copper Catalyzed Cross?Coupling of Primary Amides with Aryl and Alkyl Halides: Access to N?Arylamides as Potential Antibacterial and Anticancer Agents, 31, e202403649, Chem. Eur. J., 2025
  • 4 Saha, A., Roy, K., Mondal, S., Saha, B., Sumar, J., Sahu, S. K., Adak, L., Reusable cobalt–copper-catalyzed cross-coupling of (hetero) aryl halides with primary amides under air: investigating a new Co0/CoII-based catalytic cycle, 23, 5343-5351, Org. Biomol. Chem., 2025
  • 5 Panja, S.; Paul, B.; Saha, A.; Roy, K.; Nandi, C.; Majhi, B.; Adak, L.; Ranu, B. C., Ruthenium-Catalyzed Site-Selective Annulation of Benzoxazinones: An Easy Access to Dihydroisoquinoline Benzamide Derivatives, 31, e202500512, Chem. Eur. J., 2025
  • 6 Kundu, P.; Roy, K.; Saha, A.; Mondal, S.; Adak, L., Reusable, Efficient Manganese–Copper-Catalyzed Cross-Coupling of Aryl Halides with Aromatic Alcohols under Solvent-Minimized Conditions, 10, e01770, ChemistrySelect, 2025
  • 7 Saha, A.; Roy, K.; Banerjee, S.; Panja, S.; Khatua, M.; Mukhopadhyay; C. M., Samanta, S.; Adak, L., Room temperature palladium-catalyzed synthesis of novel unsymmetrical diamide scaffolds containing moieties of ?-ketoester as potential antibacterial, antifungal and anticancer Agents, 1322, 140177, Journal of Molecular Structure, 2025
  • 8 Roy, K.; Saha, A.; Sahoo, S.; Banerjee, Chitrangada Das Mukhopadhyay, Banerjee, S.; Adak, L., Reaction under Ball-Milling: Solvent-and Metal-Free One-Pot Diastereoselective Synthesis of Tetrahydroquinoline Derivatives as Potential Antibacterial and Anticancer Agents, 35, 2487-2495, Synlett, 2024
  • 9 Patel,A. R.; Maity, G.; Pati, T. K.; Adak, L.; Cioffi, C. L.; Banerjee, S., Hybrid Pd0.1Cu0.9Co2O4 nano-flakes: a novel, efficient and reusable catalyst for the one-pot heck and Suzuki couplings with simultaneous transesterification reactions under microwave irradiation, 12, 1496234, Frontiers in Chemistry, 2024
  • 10 Ranu, B. C.; Adak, L.; Mukherjee, N.; Ghosh, T., Benign-Metal-Catalyzed Carbon–Carbon and Carbon–Heteroatom Bond Formation, 34, 601-621, Synlett, 2023
  • 11 Roy, K.; Sahoo, S.; Saha, A.; Adak, L., Ball milling in organic transformations, 27, 153-165, Curr. Org. Chem., 2023
  • 12 Ranu, B. C.; Adak, L.; Ghosh, T., Learning Green Chemistry and its principles from Nature’s process and development of green procedures mimicking nature, 4, 127-141, Chemistry Teacher International, 2022
  • 13 Adak, L.; Kundu, D.; Roy, K.; Saha, M.; Roy, A., Reusable Iron/Iron Oxide-Based Nanoparticles Catalyzed Organic Reactions, 26, 399-417, Curr. Org. Chem., 2022
    • 14 Ranu, B. C.; Adak, L.; Mukherjee, N.; Ghosh, T., Benign-Metal-Catalyzed Carbon–Carbon and Carbon–Hetero¬atom Bond Formation, DOI: 10.1055/a-1904-0152, Synlett, 2022
  • 15 Adak, L.; Jin, M.; Saito, S.; Kawabata, T.; Itoh, T.; Ito, S.; Sharma, A. K.; Isozaki, K. Nakamura, M., Iron-Catalysed Enantioselective Carbometalation of Azabicycloalkenes, 57, 6975–6978, Chem. Commun., 2021
  • 16 Adak, L.; Hatakeyama, T.; Nakamura, M., Iron-Catalyzed Cross- Coupling Reactions Tuned by Bulky ortho-Phenylene Bisphosphine Ligands, 94, 1125–1141, Bull. Chem. Soc. Jpn., 2021
  • 17 Adak, L.; Ghosh, T., Recent Progress in Iron-Catalyzed Reactions towards the Synthesis of Bioactive Five- and Six-Membered Heterocycles, 24, 2634-2664, Curr. Org. Chem., 2020
  • 18 Ranu, B. C.; Ghosh, T.; Adak, L., Recent Progress on Carbon-Chalcogen Bond Formation Reaction Under Microwave Irradiation, 7, 40-49, Curr. Microwave Chem., 2020
  • 19 Iwamoto, T.; Okuzono, C.; Adak, L.; Jin, M. Nakamura, M., Iron-Catalysed Enantioselective Suzuki–Miyaura Coupling of Racemic Alkyl Bromides, 55, 1128–1131, Chem. Commun., 2019
  • 20 Adak, L.; Kawamura, S.; Toma, G.; Isozaki, K.; Takaya, H.; Orita, A.; Li, H. C.; Nakamura, M., Synthesis of Aryl C-Glycosides via Iron-Catalyzed Cross-Coupling of Halosugars: Stereoselective Anomeric Arylation of Glycosyl Radicals, 139, 10693– 10701, J. Am. Chem. Soc., 2017
  • 21 Sharma, A. K.; Sameera, W. M. C.; Jin, M.; Adak, L.; Okuzono, C.; Iwamoto, T.; Kato, M.; Nakamura, M.; Morokuma, K., DFT and AFIR Study on the Mechanism and the Origin of Enantioselectivity in Iron- Catalyzed Cross-Coupling Reactions, 139, 16117– 16125, J. Am. Chem. Soc., 2017
  • 22 Jin, M.; Adak, L.; Nakamura, M., Iron-Catalyzed Enantioselective Coupling of ?-Chloroesters, 11, 0861-0861, Synfacts, 2015
  • 23 Jin, M.; Adak, L.; Nakamura, M., Iron-Catalyzed Enantioselective Cross- Coupling Reactions of ?- Chloroesters with Aryl Grignard Reagents, 137, 7128– 7134, J. Am. Chem. Soc., 2015
  • 24 Takaya, H.; Nakajima, S.; Nakagawa, N.; Isozaki, K.; Imayoshi, R.; Gower, N. J.; Adak, L.; Hatakeyama, T.; Honma, T.; Nagashima, H.; Nakamura, M., Investigation of Organoiron Catalysis in Kumada–Tamao–Corriu-Type Cross-Coupling Reaction Assisted by Solution-Phase X-ray Absorption Spectroscopy, 88, 410– 418, Bull. Chem. Soc. Jpn., 2015
  • 25 Adak, L.; Yoshikai, N., Iron-Catalyzed Annulation Reaction of Arylindium Reagents and Alkynes to Produce Substituted Naphthalenes, 68, 5167– 5171, Tetrahedron, 2012
  • 26 Saha, D.; Adak, L. ; Ranu, B. C., Hydroxyapatite-Supported Cu(I)-Catalysed Cyanation of Styrenyl Bromides with K4[Fe(CN)6]: an Easy Access to Cinnamonitriles, 10, 952– 957, Org. Biomol. Chem., 2012
  • 27 Banerjee, S.; Adak, L.; Ranu, B. C., Ionic Liquid/PPh3 Promoted Cleavage of Diphenyl Disulfide and Diselenide: A Straight–Forward One-Pot Route to the Synthesis of Unsymmetrical Sulfides and Selenides, 53, 2149– 2152, Tetrahedron Lett., 2012
  • 28 Adak, L.; Yoshikai, N., Cobalt-Catalyzed Preparation of Arylindium Reagents from Aryl and Heteroaryl Bromides, 76, 7563– 7568, J. Org. Chem., 2011
  • 29 Adak, L.; Chan, W. C.; Yoshikai, N., Nickel-Catalyzed, Directing Group-Assisted [2+2+2] Cycloaddition of Imine and Alkynes, 6, 359– 362, Chem. Asian J., 2011
  • 30 Adak, L.; Bhadra, S.; Chattopadhyay, K.; Ranu, B. C., Amphiphilic Allylation of Activated Alkenes by Allyl Acetates and Allylstannanes Catalyzed by Palladium Nanoparticles, 35, 430– 437, New J. Chem., 2011
  • 31 Bhadra, S.; Adak, L.; Samanta, S.; Islam, A. K. M. M.; Mukherjee, M.; Ranu, B. C., Synthesis of Oxazines and Dioxanes from Aziridines and Epoxides, 3, 0339-0339, Synfacts, 2011
  • 32 Bhadra, S.; Adak, L. ; Samanta, S.; Islam, A. K. M. M.; Mukherjee, M.; Ranu, B. C., Alumina-Supported Cu (II), A Versatile and Recyclable Catalyst for Regioselective Ring Opening of Aziridines and Epoxides and Subsequent Cyclization to Functionalized 1,4-Benzoxazines and 1,4- Benzodioxanes, 75, 8533– 8541, J. Org. Chem., 2010
  • 33 Adak, L.; Bhadra, S.; Ranu, B. C., Palladium (0) Nanoparticle– Catalyzed sp2 C–H Activation: A Convenient Route to Alkyl–Aryl Ketones by Direct Acylation of Aryl Bromides and Iodides with Aldehydes, 51, 3811– 3814, Tetrahedron Lett., 2010
  • 34 Saha, D.; Adak, L.; Ranu, B. C., Palladium(0) Nanoparticles- Catalyzed Ligand–free Direct Arylation of Benzothiazoles via C-H Bond Functionalization, 51, 5624– 5627, Tetrahedron Lett., 2010
  • 35 Adak, L.; Chattopadhyay, K.; Ranu, B. C., Palladium Nanoparticles– Catalyzed C–N Bond Formation. A Highly Regio–and Stereoselective Allylic Amination by Allyl Acetates, 74, 3982– 3985, J. Org. Chem., 2009
  • 36 Adak, L.; Chattopadhyay, K.; Ranu, B. C., C—N Bond Formation with Palladium Nanoparticles, 8, 0937-0937, Synfacts, 2009
  • 37 Ranu, B. C.; Chatopadhyay, K.; Adak, L.; Saha, A.; Bhadra, S.; Saha, D.; Dey, R., Metal Nanoparticles as Efficient Catalysts for Organic Reactions, 81, 2337– 2354, Pure Appl. Chem., 2009
  • 38 Ranu, B. C.; Adak, L.; Chattopadhyay, K., Hydroxyapatite–Supported Palladium–Catalyzed Efficient Synthesis of (E)-2- Alkene-4-ynecarboxylic Esters, Intense Fluorescence Emission of Selected Compounds, 73, 5609– 5612, J. Org. Chem., 2008
  • 39 Samanta, S.; Adak, L.; Jana, R.; Mostafa, G.; Tunonen, H. M.; Ranu, B. C.; Goswami, S., Oxidative ortho-C–N Fusion of Aniline by OsO4. Isolation, Characterization of Oxo–Amido Osmium(VI) Complexs, and their Catalytic Activities for Oxidative C–C Bond Cleavage of Unsaturated Hydrocarbons, 47, 11062– 11070, Inorg. Chem., 2008
  • 40 Ranu, B. C.; Adak, L.; Banerjee, S., Ionic Liquid Promoted Interrupted Feist–Benary Reaction with High Diastereoselectivity, 49, 4613– 4617, Tetrahedron Lett., 2008
  • 41 Ranu, B. C.; Bhadra, S.; Adak, L., Indium (III) Chloride- Catalyzed Oxidative Cleavage of Carbon-Carbon Multiple Bonds by tert-Butyl Hydroperoxide in Water a Safer Alternative to Ozonolysis, 49, 2588– 2591, Tetrahedron Lett., 2008
  • 42 Ranu, B. C.; Chattopadhyay, K.; Adak, L., Solvent-Controlled Highly Selective Bis– and Monoallylation of Active Methylene Compounds by Allyl Acetate with Palladium(0)Nanoparticle, 9, 4595– 4598, Org. Lett., 2007
  • 43 Ranu, B. C.; Banerjee, S.; Adak, L., Regioselective Cross– Coupling of Allylindium Reagents with Activated Benzylic Bromides-A Simple and Efficient Procedure for the Synthesis of Terminal Alkenes, 48, 7374– 7379, Tetrahedron Lett., 2007
  • 44 Ranu, B. C.; Adak, L.; Banerjee, S., Halogenation of Carbonyl Compounds by an Ionic Liquid, [AcMIm]X, and Ceric Ammonium Nitrate (CAN), 60, 358– 362, Aust. J. Chem., 2007
  • 45 Ranu, B. C.; Adak, L.; Banerjee, S., Efficient Regio– and Stereo– Selective Cleavage of Aziridines and Epoxides using an Ionic Liquid as Reagent and Reaction Medium, 85, 366–371, Can. J. Chem., 2007
  • 1 Ranu, B. C.; Chattopadhyay, K.; Saha, A.; Adak, L.; Jana, R.; Bhadra, S.; Dey, R.; Saha, D., Potential of Metal Nanoparticles in Organic Reactions, 106, 12003–, Journal of Physics: Conference Series, 2008
  • 1 Adak, L.; Ghosh, T.; Ranu, B. C., C–C Bond Formation in Water Through Cross Dehydrogenative Coupling (Science of Synthesis Reference Library: Cross-Dehydrogenative Coupling, edited by D. Maiti), Thieme, Stuttgart, Germany405-437, , 2023
  • 2 Adak, L.; Sahoo, S.; Aoki, S.; Kawanaka, Y.; Nakamura, M., Iron-Catalyzed Cross-Coupling of Alkyl Electrophiles ( Science of Synthesis, Base-Metal Catalysis 2), Thieme, Stuttgart, Germany391-434, , 2023
    • 3 Ranu, B. C.; Adak, L.; Mukherjee, N.; Ghosh, T., Magnetic metal nanoparticle-catalyzed carbon-heteroatom bond formation and synthesis of related heterocycles (Magnetic Nanocatalysis Book, Synthetic Applications; ed, R. Varma and B. Banerjee), De Gruyter, Germanyhttps://doi.org/10.1515/9783110730357-001, , 2022
  • 4 Ranu, B. C.; Ghosh, T.; Adak, L.; Panja, S., Selenophenes. (Comprehensive Heterocyclic Chemistry IV, Vol-3, Editors-in-Chief: Black, D. StC; Cossy, J.; Stevens, C. V.), Oxford: Elsevier Publications,3, 653-674, , 2022
  • 5 Ranu, B. C.; Ghosh, T.; Adak, L., Recent Advances in the Synthesis of Bioactive Five- and Six-Membered Heterocycles Catalyzed by Heterogeneous Metal Catalysts, (Green Synthetic Approaches for Biologically Relevant Heterocycles Book, Vol-2. Green Catalytic Systems and Solvents, 2nd edn, Ed. G. Bramhachari), Elsevier Publications2, 11–51, , 2021

    • Patents


    # Patents Year

    Member


    LIFE MEMBERSHIP of INDIAN CHEMICAL SOCIETY

    Projects


    • Dual Transition Metal Catalysis for C-C and C-heteroatom Bond Forming Reactions:, Sponsored
      Completed
    • Synthesis of Iron Complexes and Their Catalytic Role in 1,4-Addition Reactions of Organoboron Reagents to alpha,beta-Unsaturated Carbonyl and Related Compounds, Sponsored
      Completed

    Awards


    • Awarded with Prize for Best Poster Presentation from Asutosh College, Kolkata in association with Indian Chemical Society, Year: 2017
    • The MEXT project “Integrated Research on Chemical Synthesis” Research Fellowship from Kyoto University, Japan, Year: 2014
    • JSPS Post-doctoral Research Fellowship from Japan Society for the Promotion of Science, Government of Japan, Year: 2012
    • Senior Research Fellowship (SRF) from Council of Scientific and Industrial Research (CSIR), Government of India, Year: 2007
    • Qualified Graduate Aptitude Test in Engineering (GATE), Year: 2005
    • Junior Research Fellowship (JRF) from Council of Scientific and Industrial Research (CSIR), Government of India, Year: 2005
    • Awarded University Gold Medal, Year: 2003
    • Awarded National Scholarship, Year: 2001

    Research Groups


    Keya Roy
    Ph. D.
    keyaroy107@gmail.com

    Anay Saha
    Ph. D.
    8777089636
    sahaanay75@gmail.com

    Suprakash Sahoo
    Ph. D.
    9735071228
    suprakash1561997@gmail.com

    Sampa Mondal
    Ph. D.
    sampamondal8348@gmail.com

    Puja Kundu
    Ph. D.
    pujakundupuja1999@gmail.com

    Rahul Mondal
    Ph. D.
    mondalrahulckmb@gmail.com

    Citations


    Google Scholar
    CITATION H-INDEX I-10 INDEX
    1591 21 24

    Created: 23 November 2019