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Chitrangada Das Mukhopadhyay

About


Development of novel therapeutics to translate laboratory results for a malignant brain tumor and dementia patients using a holistic approach. Our Neurobiotechnology laboratory led by Dr. Mukhopadhyay at IIEST, Shibpur has state of art infrastructural set up to carry out research to develop novel peptide-based therapeutics against cancer metastasis and neurodegenerative diseases. The Clinical microbiology laboratory is engaged in deciphering causes for Multidrug resistance in bacteria. We work together with neighboring Academic institutions of repute as well as with well-known clinicians at Medical colleges and Hospitals to solve the problem in a multidisciplinary manner. MTech students at this lab have developed electromagnetic devices to treat the above glioblastoma by creating gentle and focused hyperthermia and to treat Alzheimers’ diseases by reestablishing Ca homeostasis.

Academic Qualifications


  • M Tech,  Ph.D. (IIT, Kharagpur)
  • Postdoc ( Ohio State University, USA)

Research Statement


Diagnosis and therapy for Neuronal diseases

Clinical Microbiology

Multidrug resistance

Functional genomics, RNA interference

 

 

Latest Publications


  • 1 Bhuban Ruidas, T K Sur, Kunal Pal, Sutapa Som Chaudhury, Parash Prasad, Koel Sinha, P K Sarkar, Pritha Das, Chitrangada Das Mukhopadhyay*, Herbometallic nano-drug inducing metastatic growth inhibition in breast cancer through intracellular energy depletion, Molecular Biology Reports, 2020
  • 2 Krishna Gopal Goswami, Sourav Mete, Sutapa Som Chaudhury, Pintu Sar, Evgenii Ksendzov, Chitrangada Das Mukhopadhyay, Sergei Victorovich Kostjuk, Priyadarsi De, Self-Assembly of Amphiphilic Copolymers with Sequence Controlled Alternating Hydrophilic-Hydrophobic Pendant Side Chains, ACS Applied Polymer Materials, 2020
  • 3 Koel Sinha and C Das Mukhopadhyay*, Quantitative detection of neurotransmitter using aptamer: From diagnosis to therapeutics, 45:44, J Biosci., Indian Academy of Sciences, 2020
  • 4 N Choudhury, B Ruidas, B Saha, K Srikanth, Chitrangada Das Mukhopadhyay, P De, Multifunctional Tryptophan based fluorescent polymeric probes for sensing, Bioimaging and Removal of Cu2+ and Hg2+ ions, Polymer Chemistry, 2020
  • 5 Biswajit Saha, Bhuban Ruidas, Sourav Mete, Chitrangada Das Mukhopadhyay,* Kamal Bauri * and Priyadarsi De *, AIE-active non-conjugated poly(Nvinylcaprolactam) (2020) as a fluorescent thermometer for intracellular temperature imaging, Chemical science, 2020
  • 6 MoumitaChakraborty, Satyajit Mondal, ChristineCardin, Arnold L.Rheingold, ChitrangadaDas Mukhopadhyay, Shyamal K. Chattopadhyay*, Yb(III), Sm(III) and La(III) complexes of a tetradentate pyridoxal Schiff base ligand: Their DNA-binding activity and bio-imaging applications (2019), 175, 114167, Polyhedron, 2020
  • 7 Bhuban Ruidas, Sutapa Som Chaudhury, Kunal Pal, P K Sarkar, Chitrangada Das Mukhopadhyay*, A novel herbometallic nanodrug has the potential for antibacterial and anticancer activity through oxidative damage, Nanomedicine, 2019
  • 8 Sutapa Som Chaudhury, Achinta Sannigrahi, Mridula Nandi, Vipin K. Mishra, Priyadarsi De, Krishnananda Chattopadhyay, Sabyashachi Mishra, Jaya Sil, Chitrangada Das Mukhopadhyay*, A Novel PEGylated Block Copolymer in New Age Therapeutics for Alzheimer's Disease, Molecular Neurobiology, 2019
  • 9 Dibyendu Sain, Abhishek Manna, Chanda Kumari, Chitrangada Das Mukhopadhyay and Shyamaprosad Goswami, A Nontoxic, Bio friendly, Fluorescent Chemodosimeter for Hypochlorite Detection in Living Cells through the Oxidation of Hypochlorite on a Hydrazide System, 3: 43, 12050-12056, Chemistry Select, 2018
  • 10 Barnali Naskar, Antonio Bauzá, Antonio Frontera, Dilip K. Maiti, Chitrangada Das Mukhopadhyay and Sanchita Goswami, A versatile chemosensor for the detection of Al3+ and picric acid (PA) in aqueous solution, 47, Issue 44,, 15907-15916, Dalton Trans., 2018
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    Publications


    1 Bhuban Ruidas, T K Sur, Kunal Pal, Sutapa Som Chaudhury, Parash Prasad, Koel Sinha, P K Sarkar, Pritha Das, Chitrangada Das Mukhopadhyay*, Herbometallic nano-drug inducing metastatic growth inhibition in breast cancer through intracellular energy depletion, Molecular Biology Reports, 2020 2 Krishna Gopal Goswami, Sourav Mete, Sutapa Som Chaudhury, Pintu Sar, Evgenii Ksendzov, Chitrangada Das Mukhopadhyay, Sergei Victorovich Kostjuk, Priyadarsi De, Self-Assembly of Amphiphilic Copolymers with Sequence Controlled Alternating Hydrophilic-Hydrophobic Pendant Side Chains, ACS Applied Polymer Materials, 2020 3 Koel Sinha and C Das Mukhopadhyay*, Quantitative detection of neurotransmitter using aptamer: From diagnosis to therapeutics, 45:44, J Biosci., Indian Academy of Sciences, 2020
  • 4 N Choudhury, B Ruidas, B Saha, K Srikanth, Chitrangada Das Mukhopadhyay, P De, Multifunctional Tryptophan based fluorescent polymeric probes for sensing, Bioimaging and Removal of Cu2+ and Hg2+ ions, Polymer Chemistry, 2020
  • 5 Biswajit Saha, Bhuban Ruidas, Sourav Mete, Chitrangada Das Mukhopadhyay,* Kamal Bauri * and Priyadarsi De *, AIE-active non-conjugated poly(Nvinylcaprolactam) (2020) as a fluorescent thermometer for intracellular temperature imaging, Chemical science, 2020
  • 6 MoumitaChakraborty, Satyajit Mondal, ChristineCardin, Arnold L.Rheingold, ChitrangadaDas Mukhopadhyay, Shyamal K. Chattopadhyay*, Yb(III), Sm(III) and La(III) complexes of a tetradentate pyridoxal Schiff base ligand: Their DNA-binding activity and bio-imaging applications (2019), 175, 114167, Polyhedron, 2020
  • 7 Bhuban Ruidas, Sutapa Som Chaudhury, Kunal Pal, P K Sarkar, Chitrangada Das Mukhopadhyay*, A novel herbometallic nanodrug has the potential for antibacterial and anticancer activity through oxidative damage, Nanomedicine, 2019 8 Sutapa Som Chaudhury, Achinta Sannigrahi, Mridula Nandi, Vipin K. Mishra, Priyadarsi De, Krishnananda Chattopadhyay, Sabyashachi Mishra, Jaya Sil, Chitrangada Das Mukhopadhyay*, A Novel PEGylated Block Copolymer in New Age Therapeutics for Alzheimer's Disease, Molecular Neurobiology, 2019
  • 9 Dibyendu Sain, Abhishek Manna, Chanda Kumari, Chitrangada Das Mukhopadhyay and Shyamaprosad Goswami, A Nontoxic, Bio friendly, Fluorescent Chemodosimeter for Hypochlorite Detection in Living Cells through the Oxidation of Hypochlorite on a Hydrazide System, 3: 43, 12050-12056, Chemistry Select, 2018
  • 10 Barnali Naskar, Antonio Bauzá, Antonio Frontera, Dilip K. Maiti, Chitrangada Das Mukhopadhyay and Sanchita Goswami, A versatile chemosensor for the detection of Al3+ and picric acid (PA) in aqueous solution, 47, Issue 44,, 15907-15916, Dalton Trans., 2018
  • 11 Sutapa SomChowdhury and Chitrangada Das Mukhopadhyay*, Functional Amyloids: Interrelationship with other Amyloids and Therapeutic Assessment to Treat Neurodegenerative Diseases, Internl Jl NeuroSc, 2017
  • 12 Mukhopadhyay CD*, Ruidas B, Chaudhury SS, Role of Curcumin in Treatment of Alzheimer Disease, 4: 274, Int J Neurorehabilitation, 2017
  • 13 Barnali Naskar, Ritwik Modak, Dilip K. Maiti, Michael G. B. Drew, Chitrangada Das Mukhopadhyay, Sanchita Goswami, A Schiff base platform: structures, sensing of Zn(II), PPi in aqueous medium and anticancer activity., Dalton Transactions, 2017
  • 14 Bhadra Preetha, Das Mukhopadhyay Chitrangada and Mukherjee Sampad, Determining the effect of aflatoxin b1 using hemoglobin of human blood as interacting medium by calculation of collision energy, 5(4)ISSN: 2320-5407, 742-748, Int. J. Adv. Res., 2017
  • 15 Amit Paul, Jaya Sil and Chitrangada Das Mukhopadhyay, Gene selection for designing optimal fuzzy rule base classifier by estimating missing value, Applied Soft Computing, 2017
  • 16 Piyali Adak, Bipinbihari Ghosh, Antonio Bauz, Antonio Frontera, Alexander J. Blake, Montserrat Corbella, Chitrangada Das Mukhopadhyay and Shyamal Kumar Chattopadhyay, Catecholase activity, DNA binding and cytotoxicity studies of a Cu(II) complex of a pyridoxal schiff base: synthesis, X-ray crystal structure, spectroscopic, electrochemical and theoretical studies, 6, 86851, RSC Adv., 2016
  • 17 Aich, Krishnendu; Goswami, Shyamaprosad; Das, Sangita; Mukhopadhyay, Chitrangada; Quah, Ching Kheng; Fun, Hoong-Kun, Cd2+ triggered the FRET ‘ON’: a new molecular switch for the ratiometric detection of Cd2+ with live-cell imaging and bound X-ray structure, 54 (15), 7309–7315, Inorg. Chem., 2015
  • 18 Sima Paul, S P Goswami, Chitrangada Das Mukhopadhyay, An ESIPT based remarkable ratiomatric fluorescent chemodosimeter for very rapid detection of hydrogen sulfide in vapor phase and living cells., 39, 8940-8947, New J. Chem., 2015
  • 19 A K Mahapatra, K Maiti, S K Manna, S. Mondal, Chitrangada Das Mukhopadhyay, A cyclization-induced emission enhancement (CIEE)?based ratiometric fluorogenic and chromogenic probe for the facile detection of a nerve agent simulant DCP, 51, 9729-9732, Chem. Commun., 2015
  • 20 Krishnendu Aich, Shyamaprosad Goswami, Sangita Das and Chitrangada Das Mukhopadhyay, A new ICT and CHEF based visible light excitable fluorescent probe easily detects in vivo Zn2+, 5, 31189-31194, RSC Adv., 2015
  • 21 S P Goswami, K. Aich, S. Das, Chitrangada Das Mukhopadhyay, D. Sarkar, T.K Mondal, A new visible light excitable ICT-CHEF mediated fluorescence ‘turn on’ probe for the selective detection of Cd2+ in mixed aqueous system with live cell imaging ,, 44, 12, 5763-5770, Dalton Transactions, 2015
  • 22 AK Mahapatra, RK Maji, K Maiti, S K Manna, S. Mondal, Chitrangada Das Mukhopadhyay, S P Goswami, D. Sarkar, T K Mondal, CK Quah, H K Fun, Synthesis and Anion Sensing Properties of Novel N,O–Chelated Perimidine–BF Complex, 207, 876, Sensors and Actuators B Chemical, 2015
  • 23 AK Mahapatra, K Maiti, S K Manna, Rajkishor Maji, Chitrangada Das Mukhopadhyay, Bholanath Pakhira, Sabyasachi Sarkar, Unique Fluorogenic Ratiometric Fluorescent Chemodosimeter for Rapid Sensing of CN -in Water Chemistry ., 9 (12), 3623-3632, An Asian Journal, 2014
  • 24 AK Mahapatra, S K Manna, Kalipada Maiti, Rajkishor Maji, Chitrangada Das Mukhopadhyay, Deblina Sarkar, Tapan Kumar Mondal, Imino–phenolic–azodye appended rhodamine as a primary fluorescence “off–on” chemosensor for tin (Sn4+) in solution and in RAW cells and the recognition of sulphide by [AR–Sn]., 4(69), 36615-36622, RSC Advances, 2014
  • 25 AK Mahapatra, S K Manna, Chitrangada Das Mukhopadhyay, Debasish Mandal, Pyrophosphate-selective fluorescent chemosensor based on ratiometric tripodal-Zn(II) complex., 200, 123–131, Application in logic gates and living cells Sensors and Actuators B Chemical, 2014
  • 26 Vanda J Lisnic, Marina B Cac, B Lisnic, C Das Mukhopadhyay, Charles H. Cook, Stipan Jonjic and Joanne Trgovcich, Dual Analysis of the Murine Cytomegalovirus and Host Cell Transcriptomes Reveal New Aspects of the Virus-Host Cell Interface, 9(9), e1003611, PLoS Pathog, 2013
  • 27 Mahapatra A., Manna, S; Mandal D; Das Mukhopadhyay C., A Highly Sensitive and Selective Rhodamine-based “Off?On” Reversible Chemosensor for Tin (Sn4+) and Imaging in Living Cells., 52, Issue 19, 10825–10834, Inorg. Chem, 2013
  • 28 Mahapatra A. K., Maji R, Adhikari S. S., Das Mukhopadhyay C. and Mandal D., Ratiometric sensing of fluoride and acetate anions based on a BODIPY-azaindole platform and its application to living cell imaging ., Analyst, 2013
  • 29 K.D. Mehta, Chitrangada Das, B.D. Pandey, Leaching of copper, nickel and cobalt from Indian Ocean manganese nodules by Aspergillus niger., 105, No. 1-2, 89- 95, Hydrometallurgy, 2010
  • 30 K.D. Mehta, Chitrangada Das, Rakesh Kumar, B.D. Pandey, S.P. Mehrotra, Effect of mechano-chemical activation on bioleaching of Indian Ocean nodules by a fungus Mineral Engg ., 23:15, 1207-1212, Elseiver, 2010
  • 31 Beltramini A., Das C., Pancholi V., Modulation of cell wall structure and antimicrobial susceptibility by a Staphylococcus aureus eukaryotic-like serine/threonine kinase and phosphatase., 77: 4, 1406-1416, Infect. Immun., 2009
  • 32 Das C. and Mishra, H. N., A review on Biological control and metabolism of aflatoxin., 43: 3, 245-264, CRC Critical Review on Food Science and Nutrition, 2003
  • 33 Das C. and Mishra, H. N., Effect of Aflatoxin B1 detoxification on some in vivo and in vitro plant physiological systems., 23: 3, 311-317, Acta Physiologaea Plantarum, 2001
  • 34 Das C. and Mishra H. N., In vitro degradation of Aflatoxin B1 by horse radish peroxidase., 68, 309-313, Food Chem., 2000
  • 35 Das C. and Mishra H. N., In vitro degradation of Aflatoxin B1 in ground nut (Arachis hypogaea) meal by horse radish peroxidase., 33:4, 308-312, Food Sc. Tech., 2000
  • 36 Das C. and Mishra H. N., Effect of Aflatoxin B1 detoxification on the physicochemical properties and quality of Ground nut meal., 70:4, 483- 487, Food Chem, 2000
  • Patents


    # Patents Year

    Member


    Dr Tapas Sur

    Research Associate in Project

    Pramita Sharma

    Project Fellow

    Projects


    • The Prospect of Cancer Therapy using an inorganic Nano conjugate comprising microRNA-34 family, Sanctioned by DST Nanomission, Sponsored
      Completed
    • A biotechnological approach for rapid detection of aflatoxin in food using optical nanofibre probes, DBT, Sponsored
      Completed
    • Tissue Transglutaminase to treat brain cancer funded by DBT, GoI, Sponsored
      Completed
    • Induction of Local hyperthermia using rotatory electromagnetic field to treat brain malignancy, WB-DST, Sponsored
      Ongoing
    • Bioactivity guided fractionation of phytochemicals from medicinal plants against brain malignancy authenticated by DNA bar coding, AYUSH, GoI, Sponsored
      Ongoing

    Research Groups


    Bhuban Ruidas
    Ph. D.
    bhubo18@gmail.com

    Sutapa SomChaudhury
    Ph. D.
    somchaudhurysutapa@gmail.com

    Research:
    Neurodegenerative disease

    Koel Sinha
    Ph. D.
    ksinha2110@gmail.com

    Research:
    Detection of Neurotransmitter

    Dr Rabindranath Mazumdar
    Ph. D.
    dr.rabindranath.majumder@gmail.com

    Research:
    Drug delivery

    Citations


    Google Scholar
    CITATION H-INDEX I-10 INDEX
    1376 21 26
    Research Gate
    PUBLICATIONS CITATION H-INDEX
    36 850 14
    Scopus
    DOCUMENTS CITATION H-INDEX
    25 576 11

    Created: 23 November 2019