The Centre for Healthcare Science and Technology at IIEST, Shibpur has been introduced in year 2010 in erstwhile BESU with an objective to provide interdisciplinary research and training programs encompassing the fields of modern biology, medicine, engineering, physics, chemistry and mathematics etc. to solve important and persistent problems related to public health in the society. CHST, IIEST Shibpur strives to integrate the knowledge base generated in these various fields of study and provide a cross-discipline platform for indigenous innovation in the medical sector.
Interestingly, medical technology is a highly innovation-driven sector witnessing continuous evolution. At the same time, their human application and marketing are preceded by intensive regulatory scrutiny. Thus the bench to bedside process is highly volatile and time-consuming. Presently, extensive global research in the area depict inclination towards a systems approach to understand human physiology under normal and disease conditions, robotizing surgical procedures, miniaturizing devices for non-invasive real-time imaging of biochemical processes, creating intelligent systems for programmed delivery of drugs, genetic therapeutics, and harnessing the potential of stem cells for regenerative medicine. We at CHST, IIEST Shibpur embrace these global trends to evolve local solutions for the national healthcare system wherein exists an immediate and compelling desire for improvement in quality and efficiency.
The vision of the Center is to undertake cutting edge research and education in the areas of national healthcare importance and evolving comprehensive and integrative methods for solving the same and to make an impact on sustainable living and affordable healthcare In the process, this will emerge as internationally recognized centre of excellence for intensive teaching and research in areas of biological and biomedical engineering and collaborate with other departments of the institute, industrial enterprises and relevant medical, technological, management, or academic institutions. The centre will follow the principle that most biomedical technologies essentially require intensive participation of different types of stakeholders and appropriate strategies be designed to evolve a model wherein multiple stakeholders can deliver impactful technological outputs. To realize its vision and accomplish its mission, the centre will have the following specific activities: -
|1||Master of Technology (M. Tech.)
Safety and Occupational Health
M Tech: 2- Year course on Safety and Occupational Health
|2||Master of Technology (M. Tech.)
M Tech Biomedical Engineering: a 2-year curriculum
|3||Doctor of Philosophy (Ph. D.)||
Biomaterials, Neuroscience, Cancer Biology, Microbiology
|1||Biomaterials, Biofabrication and Drug Delivery|
|2||Biomedical Instrumentation & Signal Processing||
Prof Tibarewala has about 40 years of professional experience in the field of Biomedical Engineering since April 1977. Over
|3||Brain malignancy, Neurodegenerative diseases and therapeutics||
Ongoing Research at Neurobiotechnology Laboratory
Development of novel therapeutics to translate laboratory results for a malignant brain tumour and dementia patients using a holistic approach. Our Neurobiotechnology laboratory at IIEST, Shibpur has state of art infrastructural set up to carry out research to develop novel peptide-based therapeutics against cancer metastasis and amyloid based diseases. We work together with Dept of chemistry, computer sc, mathematics at IIEST and with premiere Institutes like CGCRI, Kolkata, JU, CU, IISER, Kolkata, IIT Kharagpur and IICB, Kolkata as well as with well-known clinicians at Hospitals at Kolkata to solve the problem in a multidisciplinary manner. MTech students at this lab have developed electromagnetic devices to treat the above glioblastoma by creating gentle and focused hyperthermia and to treat Alzheimers’ diseases by re-establishing Ca homeostasis.
|4||Clinical Microbiology and multidrug resistance||
Clinical microbiology Laboratory focuses on basic, translational, and clinical research on antimicrobial resistance of microbial strains that are emerging public health threats such as drug-resistant Staphylococcus aureus. Here, researchers seek to understand the fundamental causes of resistance. Novel investigations are currently being conducted, including those on the basic biology of the organism and disease progression studies, host pathogen interaction as well as the advantages and shortcomings of current antibiotics.
|5||Early Cancer detection|
|6||Functional genomics, RNA interference||
The objective of this lab is to understand how cellular pathways, the role of regulatory gene sequences which are reshaped in diseases using new high throughput techniques, protein-protein and genetic interaction mapping platforms and computational approaches for integrating experimental data with larger pictures of pathways and networks. The major focus of the lab is on developing precision therapies in cancer. Role of small regulatory RNAs, RNA interference studies, application of next-generation sequencing is the other areas of focus.
|8||Safety and Health Industries||
Application of nanotechnology for industrial safety. Safety Hazard modelling. HAZOP Integration. Project Engineering. Air pollution. Materials development. Particulate technology. Non-conventional Energy. Reaction kinetics modelling. Agglomeration.
Effect of Occupational hazards, whole-body vibration on human health and several cardiovascular diseases, CNS diseases and their remedy.
|9||Stem Cell and regenerative medicine||
|10||Tissue engineering, Implant designing and 3D printing||
Our principal area of focus is to fabricate functional materials for medical implants/ devices applications. We seek to understand material properties that influence cellular behaviour, explore different advanced fabrication techniques and undertake means to evolve quantitative relations for explaining cell-material interactions.
We extensively employ the electrospinning and bioprinting technique to generate nano- and microstructures containing bioactive agents for wound healing, hemostasis, tissue engineering and cellular actuation applications.
We are interested in cells and blood vessels in relation to human disease; mainly Stroke, Aging and other Neurodegenerative Diseases, Tumor microenvironment and Tissue Regeneration.
Especially, endothelial cells, pericytes, smooth muscle cells, astrocytes, microglia, neurons and oligodendrocytes along with extracellular matrix, the complete vascular repertoire is of particular interest. We explore various molecular biology, advanced microscopy techniques to address various research questions.